top of page


Public·24 members

The Domestic

Domestic policy staff have existed in the White House since the 1960s. President Lyndon B. Johnson assigned a senior-level aide to organize staff and develop domestic policy. In 1970, President Richard M. Nixon issued an executive order that created the Office of Policy Development, a large White House office with jurisdiction over economic and domestic policy. President William J. Clinton split the office, forming the current Domestic Policy Council and the National Economic Council.

The Domestic


Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The dog is of particular interest because it provides important evolutionary information and because existing breeds show great phenotypic diversity for morphological, physiological and behavioural traits. We use sequence comparison with the primate and rodent lineages to shed light on the structure and evolution of genomes and genes. Notably, the majority of the most highly conserved non-coding sequences in mammalian genomes are clustered near a small subset of genes with important roles in development. Analysis of SNPs reveals long-range haplotypes across the entire dog genome, and defines the nature of genetic diversity within and across breeds. The current SNP map now makes it possible for genome-wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health.

You are a domestic worker if you provide services related to the care of people in the home, or maintain private households or their premises. Domestic workers include nannies, childcare providers, caregivers and personal attendants, housekeepers, cooks, and other household workers.

If you work in the home but you are NOT a personal attendant, then you are not covered by the Domestic Worker Bill of Rights. However, regular overtime protections apply under Wage Order No. 15, which sets overtime protections for domestic workers who are not personal attendants. There are different overtime protections depending on the type of work performed:

Note that workers in the public housekeeping industry who devote more than 20% of their time to duties other than the work of a personal attendant are not considered personal attendants under this wage order. This specific subcategory of domestic workers is entitled to normal overtime protections (as specified in the Wage Order No. 5): overtime pay (1.5 x the regular rate of pay) for hours worked in excess of eight (8) hours in a day or 40 regular hours in a week. They are also entitled to double time (2 x the regular rate of pay) for hours worked over 12 in a day or for hours worked over eight (8) on the seventh consecutive day of the workweek (in addition to regular overtime for the first eight (8) hours worked on the seventh consecutive day).

Yes. Meal and lodging credits can be applied. However, an employer must abide by the limits specified in Wage Order No. 15. That is, meals or lodging may only be credited against the minimum wage if the employer and the employee enter into a voluntary written agreement before the work is performed. (This requirement applies to all types of domestic workers.)

Domestic abuse, also called "domestic violence" or "intimate partner violence", can be defined as a pattern of behavior in any relationship that is used to gain or maintain power and control over an intimate partner. Abuse is physical, sexual, emotional, economic or psychological actions or threats of actions that influence another person. This includes any behaviors that frighten, intimidate, terrorize, manipulate, hurt, humiliate, blame, injure, or wound someone. Domestic abuse can happen to anyone of any race, age, sexual orientation, religion, or gender. It can occur within a range of relationships including couples who are married, living together or dating. Domestic violence affects people of all socioeconomic backgrounds and education levels.

Physical and sexual assaults, or threats to commit them, are the most apparent forms of domestic abuse and violence and are usually the actions that allow others to become aware of the problem. However, regular use of other abusive behaviors by the abuser, when reinforced by one or more acts of physical violence, make up a larger system of abuse. Although physical assaults may occur only once or occasionally, they instill the fear of future violent attacks and allow the abuser to take control of the victim's life and circumstances.

Studies of the domestic cat have contributed to many scientific advances, including the present understanding of the mammalian cerebral cortex. A practical capability for cat transgenesis is needed to realize the distinctive potential of research on this neurobehaviorally complex, accessible species for advancing human and feline health. For example, humans and cats are afflicted with pandemic AIDS lentiviruses that are susceptible to species-specific restriction factors. Here we introduced genes encoding such a factor, rhesus macaque TRIMCyp, and eGFP, into the cat germline. The method establishes gamete-targeted transgenesis for the first time in a carnivore. We observed uniformly transgenic outcomes, widespread expression, no mosaicism and no F1 silencing. TRIMCyp transgenic cat lymphocytes resisted feline immunodeficiency virus replication. This capability to experimentally manipulate the genome of an AIDS-susceptible species can be used to test the potential of restriction factors for HIV gene therapy and to build models of other infectious and noninfectious diseases.

The two key approaches for generating transgenic mice are DNA injection into fertilized embryo pronuclei and injection of genetically modified embryonic stem cell (ESC) lines into blastocysts. However, in nonrodent mammals, pronuclear injection is very inefficient, and the second method is blocked by the lack of germline-competent ESCs. Transgenesis with germline transmission has been achieved in some mammals by microinjecting lentiviral vectors into oocytes or single-cell zygotes18. This has not been achieved in any carnivore species. Here we performed oocyte-targeted lentiviral transgenesis in the domestic cat.

Cat transgenesis could have additional impact. As we recently proposed, the domestic cat may have potential for modeling HIV-1 disease itself because, except for entry receptors, the cat genome can supply the dependency factors needed for HIV-1 replication10. This is a fundamental difference compared to the mouse22. Gene knockdowns and targeting are foreseeable by combining our approach with current technologies. Furthermore, transgenesis in this accessible, abundant species with intermediate size and complex neurobehavioral repertoire will permit other human-relevant models in areas such as neurobiology, where the cat is already a paramount model. Studies in the cat have revealed much of the present knowledge on organization of the mammalian brain, in particular the visual cortex23,24,25,26,27; work in this area has been critical to unraveling the neural mechanisms of vision. Although transgenesis in this species will not be as common as in rodents, the creation of a small number of lines with genetic tools could build on the large knowledge base in the species to dramatically alter capability for understanding the cerebral cortex.

The domestic cat is seasonally polyestrous and positively photoperiodic, with seasonality controlled by the duration of light31. Manipulation of day length is used to induce estrus32 and a 14 h light and 10 h dark diurnal cycle was maintained in the facility, with light onset at 06:00. A vasectomized male, verified to be azoospermic, was provided to embryo-recipient females for ad lib mating as shown in Figure 1a.

There is no court fee to file to ask for a domestic violence restraining order, and you do not have to have a lawyer. This guide will take you step-by-step through the process of asking for a restraining order. The whole process can last a few weeks or months, depending on how complicated your case is. Cases involving children and property may be more complicated.

Welcome to the Domestic Violence Action Center Website. Here you will be able to find out who we are, information about our services, get answers to questions about domestic violence, and find out ways to help or get help.

IMPORTANT: This information is instructional only. It is not legal advice. For information relevant to your domestic partnership and/or family-related issues, you should consult with a private attorney.

The Court's ruling in Obergefell v. Hodges did not invalidate or change any of the California Family Code sections related to registered domestic partners. Domestic partnership registrations are different from marriage licenses. The California Secretary of State's office will continue to process Declarations of Domestic Partnership, Notices of Termination of Domestic Partnership and other related filings as permitted by state law. County governments process marriage licenses. If you have questions about how the Supreme Court's decision may apply to your circumstances, please consult with a private attorney.

Yes. A person under 18 who otherwise meets the requirements for a domestic partnership, other than the requirement of being at least 18, may establish a domestic partnership if the person under 18 has obtained written consent of the parents or guardian of the underage person, and has obtained a court order granting permission to the underage person to establish a domestic partnership. A certified copy of the order must be filed with the California Secretary of State with the Declaration of Domestic Partnership.

If you and your partner are over 18, or one or both partners are under 18 and have obtained a court order granting permission to establish a domestic partnership, and are of the same sex, or are opposite sex and one partner is at least 62 and meet the requirements of California Family Code section 297, you may register a domestic partnership with the California Secretary of State. You may register by completing a Declaration of Domestic Partnership Form NP/SF DP-1, having both partners' signatures notarized, and submitting the form with the appropriate fee to the California Secretary of State. 041b061a72


Welcome to the group! You can connect with other members, ge...
Group Page: Groups_SingleGroup
bottom of page